What is Pregnenolone?

The short answer

Pregnenolone is a hormone that the body makes, and that can also be made in a lab.

  • What it is

    Steroid made from cholesterol; the starting point for other steroid hormones.

  • What people look into

    Testosterone, menopause

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What it is

Type
Steroid hormone precursor (neurosteroid; not a peptide)
Also known as
pregnenolone micronized
How it works
Steroid made from cholesterol; the starting point for other steroid hormones.

Regulatory status

Supplement How we label status

As of October 4, 2026, Pregnenolone is sold in the US as a dietary supplement.

See Pregnenolone in the Index →

Federal (FDA)
Not an approved drug; sold OTC as a dietary supplement
503A compounding
Category 1 (503A); 503B Category 3 (as of May 14, 2026)
WADA 2026
Not named

References

Sources as of October 4, 2026

  1. FDA: www.fda.gov/media/94155/download
  2. FDA: www.fda.gov/media/94164/download
  3. WADA: www.wada-ama.org/sites/default/files/2025-09/2026list_en_final_clean_september_2025.pdf