What is Emideltide (DSIP)?

The short answer

Emideltide, or DSIP, is a small peptide, a chain of nine amino acids.

  • What it is

    Small neuropeptide made of nine amino acids.

  • What people look into

    Sleep

Get updates on Emideltide (DSIP)

What it is

Type
Nonapeptide
Also known as
delta sleep inducing peptide
How it works
Small neuropeptide made of nine amino acids.

Regulatory status

Not FDA-approved How we label status

As of October 4, 2026, Emideltide (DSIP) is not FDA-approved for any use and is not on FDA's 503A bulks list.

See Emideltide (DSIP) in the Index →

Federal (FDA)
Not FDA-approved
503A compounding
No category (nomination withdrawn; removed from Cat 2 2026-04-22); not on 216.23 as of 2026-10-07; not an approved-drug component (as of October 7, 2026)
PCAC history
2026-07-24: NOT recommended 6-7-1 (free base and acetate; uses reviewed: opioid withdrawal, chronic insomnia, narcolepsy; count as read into FDA's meeting recording; written minutes not posted as of 2026-10-04); FDA staff: against

Timeline

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Timeline table
DateWhat happenedSource
Federal Register notice of an FDA Pharmacy Compounding Advisory Committee meeting lists emideltide (DSIP) among bulk drug substances under consideration for the 503A bulks list.Federal Register, event of April 16, 2026, on federalregister.gov
FDA presentations for the Pharmacy Compounding Advisory Committee meeting cover emideltide (DSIP) as a bulk drug substance under consideration for the 503A bulks list.FDA, event of July 24, 2026, on fda.gov

References

Sources as of October 4, 2026

  1. FDA: www.fda.gov/advisory-committees/advisory-committee-calendar/july-23-24-2026-meeting-pharmacy-compounding-advisory-committee-07232026
  2. FDA: www.fda.gov/media/193344/download
  3. FDA: www.fda.gov/media/193342/download
  4. FDA: www.fda.gov/media/94155/download
  5. FDA: www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks
  6. YouTube: youtube.com/live/xXM5ecHxlMU
  7. eCFR: www.ecfr.gov/current/title-21/chapter-I/subchapter-C/part-216/subpart-B/section-216.23
  8. FDA: api.fda.gov/drug/drugsfda.json