What is GHK-Cu (copper tripeptide)?

The short answer

GHK-Cu is a tiny peptide, three amino acids joined to copper, found in human blood.

  • What it is

    Copper-binding tripeptide found in plasma.

  • What people look into

    Skin and hair

Get updates on GHK-Cu (copper tripeptide)

What it is

Type
Copper tripeptide (glycyl-histidyl-lysine copper)
Also known as
copper peptide, copper tripeptide-1, glycyl-l-histidyl-l-lysine copper
How it works
Copper-binding tripeptide found in plasma.

Regulatory status

Cosmetic How we label status

As of October 4, 2026, GHK-Cu (copper tripeptide) is sold in the US as a cosmetic.

See GHK-Cu (copper tripeptide) in the Index →

Federal (FDA)
Not FDA-approved as a drug; cosmetic ingredient (topical)
503A compounding
Non-injectable: Category 1 (removed 2026-04-22; 'will be added back'); injectable: no category (as of May 14, 2026)
PCAC history
Scheduled: PCAC 'before the end of February 2027' (no date set)

Timeline

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Timeline table
DateWhat happenedSource
FDA list of bulk drug substances nominated under section 503A, updated May 14, 2026, adds GHK-Cu back to category 1 (under evaluation) except for injectable routes.FDA, event of May 14, 2026, on fda.gov

US enforcement actions

1 US enforcement action, in 2026.

Actions by US federal and state agencies whose documents name GHK-Cu (copper tripeptide). Each row links to the government's own document.

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US enforcement actions table
DateAgencyActionDocument
US Justice DepartmentIndictmentJustice Department document, indictment, April 1, 2026, on justice.gov

Forms and brands

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Forms and brands table
NameKindStatusFDA statusAs of
GHK-Cu (injectable)FormNot FDA-approvedNot FDA-approved
GHK-Cu (topical cosmetic)FormCosmeticCosmetic (not a drug when sold with appearance claims)

References

Sources as of October 4, 2026

  1. FDA: www.fda.gov/media/94155/download