What is LGD-4033 (ligandrol)?

The short answer

LGD-4033 is a lab-made pill that is studied in research on the same system as male hormones.

  • What it is

    Non-steroidal pill that binds the androgen receptor in a selective way.

  • What people look into

    Muscle and exercise

Get updates on LGD-4033 (ligandrol)

What it is

Type
Selective androgen receptor modulator (SARM), non-steroidal
Also known as
vk5211, anabolicum
How it works
Non-steroidal pill that binds the androgen receptor in a selective way.

Regulatory status

Not FDA-approved How we label status

As of October 4, 2026, LGD-4033 (ligandrol) is not FDA-approved for any use and is not on FDA's 503A bulks list.

See LGD-4033 (ligandrol) in the Index →

Federal (FDA)
Not FDA-approved; excluded from the dietary supplement definition under 201(ff)(3) (FDA ingredient directory categories 2, 4)
503A compounding
No category; not on 216.23 as of 2026-10-07 (as of October 7, 2026)
WADA 2026
S1.2 (named LGD-4033 (ligandrol))

US enforcement actions

2 US enforcement actions since 2023.

Actions by US federal and state agencies whose documents name LGD-4033 (ligandrol). Each row links to the government's own document.

Scroll sideways to see all columns.

US enforcement actions table
DateAgencyActionDocument
FDAWarning letterFDA document, warning letter, December 12, 2025, on fda.gov
FDAWarning letterFDA document, warning letter, June 12, 2023, on fda.gov

References

Sources as of October 4, 2026

  1. FDA: www.fda.gov/food/dietary-supplements/information-select-dietary-supplement-ingredients-and-other-substances
  2. FDA: www.fda.gov/consumers/consumer-updates/fda-warns-use-selective-androgen-receptor-modulators-sarms-among-teens-young-adults
  3. FDA warning letter, December 12, 2025
  4. FDA warning letter, June 12, 2023
  5. WADA: www.wada-ama.org/sites/default/files/2025-09/2026list_en_final_clean_september_2025.pdf
  6. eCFR: www.ecfr.gov/current/title-21/chapter-I/subchapter-C/part-216/subpart-B/section-216.23