What is Mechano growth factor (MGF)?

The short answer

Mechano growth factor is a peptide, a short chain of amino acids.

  • What it is

    Mechano growth factor (MGF): IGF-1 splice-variant peptide.

  • What people look into

    Muscle and exercise

Get updates on Mechano growth factor (MGF)

What it is

Also known as
igf-1ec

Regulatory status

Not FDA-approved How we label status

As of October 4, 2026, Mechano growth factor (MGF) is not FDA-approved for any use and is not on FDA's 503A bulks list.

See Mechano growth factor (MGF) in the Index →

Federal (FDA)
Not FDA-approved
503A compounding
Category 3 (since 2023-09-29); not on 216.23 as of 2026-10-07 (as of October 7, 2026)
WADA 2026
S2.3

Timeline

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Timeline table
DateWhat happenedSource
FDA list of bulk drug substances nominated under section 503A, updated May 14, 2026, places mechano growth factor (MGF) in category 3, nominated without adequate support.FDA, event of May 14, 2026, on fda.gov

References

Sources as of October 4, 2026

  1. FDA: www.fda.gov/media/94155/download
  2. WADA: www.wada-ama.org/sites/default/files/2025-09/2026list_en_final_clean_september_2025.pdf
  3. eCFR: www.ecfr.gov/current/title-21/chapter-I/subchapter-C/part-216/subpart-B/section-216.23