What is Naltrexone?

The short answer

In the US, you need a prescription to get Naltrexone.

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What it is

Type
Opioid antagonist (not a peptide)
Also known as
naltrexone tablets, vivitrol

Regulatory status

FDA-approved (Rx) How we label status

As of October 7, 2026, Naltrexone is an FDA-approved prescription drug for alcohol dependence; blocking the effects of opioids; preventing relapse to opioid dependence after detox (Vivitrol); chronic weight management with bupropion (Contrave).

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Federal (FDA)
Approved Rx (ReVia NDA018932 1984, disc.; generic 50 mg tablets; Vivitrol NDA021897 2006, extended-release injection; with bupropion in Contrave NDA200063 2014)
503A compounding
Approved-drug component (not in any 503A category) (as of May 14, 2026)
WADA 2026
Not named

References

Sources as of October 7, 2026

  1. DailyMed: dailymed.nlm.nih.gov/dailymed/drugInfo.cfm (1 of 3)
  2. DailyMed: dailymed.nlm.nih.gov/dailymed/drugInfo.cfm (2 of 3)
  3. DailyMed: dailymed.nlm.nih.gov/dailymed/drugInfo.cfm (3 of 3)
  4. FDA: www.fda.gov/media/94155/download
  5. WADA: www.wada-ama.org/sites/default/files/2025-09/2026list_en_final_clean_september_2025.pdf