What is Palopegteriparatide?

The short answer

Palopegteriparatide is a peptide, a short chain of amino acids. In the US, you need a prescription to get Palopegteriparatide.

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What it is

Type
Long-acting PTH(1-34) prodrug (peptide)
Also known as
yorvipath
How it works
Steady PTH replacement for hypoparathyroidism.

Regulatory status

FDA-approved (Rx) How we label status

As of October 4, 2026, Palopegteriparatide is an FDA-approved prescription drug for hypoparathyroidism in adults.

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Federal (FDA)
Approved Rx (Yorvipath NDA216490, 2024)
503A compounding
Approved-drug component (not in any 503A category) (as of May 14, 2026)

References

Sources as of October 4, 2026

  1. DailyMed: dailymed.nlm.nih.gov/dailymed/drugInfo.cfm