What is Plecanatide?
The short answer
Plecanatide is a peptide, a short chain of amino acids. In the US, you need a prescription to get Plecanatide.
- 1 source
- Status as of
- How we source
- Ellum doesn't sell peptides.
Get updates on Plecanatide
What it is
- Type
- Guanylate cyclase-C agonist (oral peptide)
- Also known as
- trulance
- How it works
- Draws fluid into the gut to relieve constipation.
Regulatory status
FDA-approved (Rx) How we label status
As of October 4, 2026, Plecanatide is an FDA-approved prescription drug for chronic idiopathic constipation; IBS with constipation.
- Federal (FDA)
- Approved Rx (Trulance NDA208745, 2017)
- 503A compounding
- Approved-drug component (not in any 503A category) (as of May 14, 2026)
References
Sources as of October 4, 2026