What is Spermidine?

The short answer

Spermidine is a natural compound found in many living things and in foods like wheat germ and soy.

  • What it is

    Natural polyamine in wheat germ and soy; studied for autophagy.

  • What people look into

    Aging

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What it is

Type
Polyamine (supplement)
Also known as
spermidine trihydrochloride, wheat germ spermidine
How it works
Natural polyamine in wheat germ and soy; studied for autophagy.

Regulatory status

Supplement How we label status

As of October 4, 2026, Spermidine is sold in the US as a dietary supplement.

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Federal (FDA)
Not an approved drug; sold as a dietary supplement (GRAS notice GRN 889 closed at notifier's request 2020)
WADA 2026
Not named

References

Sources as of October 4, 2026

  1. FDA: hfpappexternal.fda.gov/Scripts/Fdcc/index.cfm
  2. FDA: www.fda.gov/media/193536/download