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Tesamorelin / ipamorelin stack: what's in it

By Ellum EditorialPublished Updated AI use

The short answer

Tesamorelin / ipamorelin stack combines Tesamorelin and Ipamorelin.

  • What it is

    GH-axis stack (GHRH analog + ghrelin agonist).

  • What people look into

    Weight, muscle and exercise, aging, sleep

    Results for one compound don't tell you what the two do together.

The parts

  • Tesamorelin Index

    FDA-approved (Rx)

    WADA 2026: S2.2.4

    Papers on animals1
    Lab-dish (cell) papers1
    Papers PubMed tags as about people54
    Registered trials (ClinicalTrials.gov)17 of 23 search results name Tesamorelin
    Randomized trials in people21

  • Ipamorelin Index

    Not FDA-approved

    WADA 2026: S2.2.4

    Papers on animals20
    Lab-dish (cell) papers1
    Papers PubMed tags as about people22
    Registered trials (ClinicalTrials.gov)2 of 3 search results name Ipamorelin
    Randomized trials in people2

Bars are counts of papers or trials; a longer bar means more studies, not better results. Study counts auto-counted from PubMed tags and ClinicalTrials.gov in the Ellum research database, as of October 6, 2026 (not reviewed; a paper can carry more than one tag). Papers PubMed tags as about people: includes reviews and case reports; not randomized trials. All bars share one scale. Each count is for that part alone.

What's in it

Tesamorelin is a lab-made form of the hormone that tells the body to make growth hormone.[1] Stimulates the pituitary to release growth hormone.[1]

Ipamorelin is a short chain of five amino acids that is made in a lab.[2] Ghrelin-receptor agonist that releases GH.[2]

Regulatory status by component

Not FDA-approved How we label status

Status as of October 4, 2026

As a combination
No category as a combination (see components)
  • Tesamorelin: as of October 4, 2026 · source
  • Ipamorelin: as of October 4, 2026 · source

Timeline

Scroll sideways to see all columns.

DateWhat happenedSource
FTC notice in the Federal Register of the HISA Anti-Doping and Medication Control Rule (horseracing) lists ipamorelin and tesamorelin as banned substances.Federal Register
FTC notice in the Federal Register of the HISA Anti-Doping and Medication Control Rule (horseracing) lists ipamorelin and tesamorelin as banned substances.Federal Register
FDA warning letter to an online seller names a product described as a blend of tesamorelin and ipamorelin among products FDA states are unapproved new drugs.FDA
FDA warning letter to an online seller quotes the seller's webpage describing a product as a blend of tesamorelin and ipamorelin.FDA

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The research on Tesamorelin / ipamorelin stack

Key facts

Also known as: tesamorelin ipamorelin, tesa ipa, tesa/ipa, tesa ipa blend

Parts
Tesamorelin and Ipamorelin
Route
injectable

References

  1. dailymed.nlm.nih.gov
  2. www.fda.gov

Status sources

Sources as of October 4, 2026

  1. DailyMed: dailymed.nlm.nih.gov/dailymed/drugInfo.cfm
  2. FDA: www.fda.gov/media/94155/download

What this doesn’t establish

Results for one compound don't tell you what the two do together.