What is Ziconotide?

The short answer

Ziconotide is a peptide, a short chain of amino acids. In the US, you need a prescription to get Ziconotide.

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What it is

Type
N-type calcium channel blocker (conotoxin peptide)
Also known as
prialt

Regulatory status

FDA-approved (Rx) How we label status

As of October 4, 2026, Ziconotide is an FDA-approved prescription drug for severe chronic pain (intrathecal).

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Federal (FDA)
Approved Rx (Prialt NDA021060, 2004)
503A compounding
Approved-drug component (not in any 503A category) (as of May 14, 2026)

References

Sources as of October 4, 2026

  1. DailyMed: dailymed.nlm.nih.gov/dailymed/drugInfo.cfm
  2. FDA: www.fda.gov/media/94164/download