What is Afamelanotide?

The short answer

Afamelanotide is a peptide, a short chain of amino acids. In the US, you need a prescription to get Afamelanotide.

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What it is

Type
Alpha-MSH analog (peptide implant)
Also known as
scenesse, melanotan 1, melanotan i

Regulatory status

FDA-approved (Rx) How we label status

As of October 4, 2026, Afamelanotide is an FDA-approved prescription drug for phototoxic reactions in erythropoietic protoporphyria.

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Federal (FDA)
Approved Rx (Scenesse NDA210797, 2019)
503A compounding
Approved-drug component (not in any 503A category) (as of May 14, 2026)

References

Sources as of October 4, 2026

  1. DailyMed: dailymed.nlm.nih.gov/dailymed/drugInfo.cfm