What is KPV?

The short answer

KPV is a tiny lab-made peptide, the last three amino acids of a hormone the body makes.

  • What it is

    Tripeptide matching the tail end of the hormone alpha-MSH.

  • What people look into

    Muscle and exercise, skin and hair

Get updates on KPV

What it is

Type
Alpha-MSH C-terminal tripeptide
Also known as
kpv peptide, lys-pro-val, alpha-msh 11-13
How it works
Tripeptide matching the tail end of the hormone alpha-MSH.

Regulatory status

Not FDA-approved · advisory vote July 2026 · no FDA decision How we label status

As of October 4, 2026, KPV is not FDA-approved. On July 23, 2026, FDA's compounding advisory committee voted to recommend adding it to the 503A bulks list; FDA staff had recommended against it. FDA has not proposed that change.

See KPV in the Index →

Federal (FDA)
Not FDA-approved
503A compounding
No category since 2026-04-22 (nomination withdrawn); PCAC recommended 2026-07-23/24; no proposed rule as of 2026-10-04 (as of October 4, 2026)
PCAC history
2026-07-23: recommended 8-6-1 (free base and acetate; uses reviewed: wound healing, inflammatory conditions; count as read into FDA's meeting recording; written minutes not posted as of 2026-10-04); FDA staff: against

Timeline

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Timeline table
DateWhat happenedSource
Federal Register notice of an FDA Pharmacy Compounding Advisory Committee meeting lists KPV among bulk drug substances under consideration for the 503A bulks list.Federal Register, event of April 16, 2026, on federalregister.gov
FDA presentations for the Pharmacy Compounding Advisory Committee meeting cover KPV as a bulk drug substance under consideration for the 503A bulks list.FDA, event of July 23, 2026, on fda.gov

References

Sources as of October 4, 2026

  1. FDA: www.fda.gov/advisory-committees/advisory-committee-calendar/july-23-24-2026-meeting-pharmacy-compounding-advisory-committee-07232026
  2. FDA: www.fda.gov/media/193346/download
  3. FDA: www.fda.gov/media/193342/download
  4. Federal Register: www.federalregister.gov/documents/2026/04/16/2026-07361/pharmacy-compounding-advisory-committee-notice-of-meeting-establishment-of-a-public-docket-request
  5. FDA: www.fda.gov/media/94155/download
  6. FDA: www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks
  7. YouTube: youtube.com/live/DhDC0DAYdBI