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Cagrilintide / tirzepatide stack: what's in it

By Ellum EditorialUpdated AI use

The short answer

Cagrilintide / tirzepatide stack combines Cagrilintide and Tirzepatide.

  • What it is

    Amylin analog added to tirzepatide.

  • What people look into

    Weight

    Results for one compound don't tell you what the two do together.

The parts

  • Cagrilintide Index

    Investigational (phase 3)

  • Tirzepatide Index

    FDA-approved (Rx)

    WADA 2026: Not prohibited (monitoring)

    Papers on animals74
    Lab-dish (cell) papersnone found
    Papers PubMed tags as about people1,285
    Registered trials (ClinicalTrials.gov)240 of 295 search results name Tirzepatide
    Randomized trials in people132

Bars are counts of papers or trials; a longer bar means more studies, not better results. Study counts auto-counted from PubMed tags and ClinicalTrials.gov in the Ellum research database, as of October 6, 2026 (not reviewed; a paper can carry more than one tag). Papers PubMed tags as about people: includes reviews and case reports; not randomized trials. All bars share one scale. Each count is for that part alone.

Regulatory status by component

Not FDA-approved How we label status

  • As of October 4, 2026, Cagrilintide is not FDA-approved for any use and is not on FDA's 503A bulks list. It is in phase 3 trials. See Cagrilintide in the Index →
  • As of October 4, 2026, Tirzepatide is an FDA-approved prescription drug for type 2 diabetes; cardiovascular risk reduction in adults with type 2 diabetes at high risk for major adverse cardiovascular events, Mounjaro only; chronic weight management; obstructive sleep apnea with obesity. See Tirzepatide in the Index →

Status as of October 4, 2026

As a combination
No category as a combination (see components)
  • Cagrilintide: as of October 4, 2026 · source
  • Tirzepatide: as of October 4, 2026 · source

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The research on Cagrilintide / tirzepatide stack

Key facts

Also known as: cagri tirz, cagrilintide tirzepatide

Parts
Cagrilintide and Tirzepatide
Route
injectable

References

Status sources

Sources as of October 4, 2026

  1. FDA: www.fda.gov/drugs/drug-alerts-and-statements/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss
  2. DailyMed: dailymed.nlm.nih.gov/dailymed/drugInfo.cfm

What this doesn’t establish

Results for one compound don't tell you what the two do together.