What is TMG (betaine)?

The short answer

TMG, also called betaine, is a natural compound found in beets, spinach and whole grains.

  • What it is

    Supplies methyl groups.

  • What people look into

    Aging

Get updates on TMG (betaine)

What it is

Type
Methyl donor (not a peptide)
Also known as
trimethylglycine
How it works
Supplies methyl groups.

Regulatory status

Supplement How we label status

As of October 4, 2026, TMG (betaine) is sold in the US as a dietary supplement.

See TMG (betaine) in the Index →

Federal (FDA)
Dietary supplement (DSHEA)

References

Sources as of October 4, 2026

  1. DailyMed: dailymed.nlm.nih.gov/dailymed/drugInfo.cfm
  2. Regulations.gov: www.regulations.gov/document/FDA-2015-S-0024-1317